内容摘要：“Aid distribution has become a death trap,” the head of the United Nations

“Aid distribution has become a death trap,” the head of the United Nations

Gene therapies, which can be extremely expensive to develop, generally target more common disorders in part for simple financial reasons: more patients mean potentially more sales, which can help pay the development costs and generate more profit. The first CRISPR therapy, for example, treats sickle cell disease, a painful blood disorder affecting millions worldwide.

Musunuru said his team’s work —— showed that creating a custom treatment doesn’t have to be prohibitively expensive. The cost was “not far off” from the $800,000-plus for an average liver transplant and related care, he said.“As we get better and better at making these therapies and shorten the time frame even more, economies of scale will kick in and I would expect the costs to come down,” Musunuru said.

Scientists also won’t have to redo all the initial work every time they create a customized therapy, Bhoopalan said, so this research “sets the stage” for treating other rare conditions.Carlos Moraes, a neurology professor at the University of Miami who wasn’t involved with the study, said research like this opens the door to more advances.

“Once someone comes with a breakthrough like this, it will take no time” for other teams to apply the lessons and move forward, he said. “There are barriers, but I predict that they are going to be crossed in the next five to 10 years. Then the whole field will move as a block because we’re pretty much ready.”

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.The soldier said he found Billie in Gaza’s southern city of Rafah — about 9 miles (15 kilometers) from the Kibbutz — days earlier, and she immediately gravitated toward his troops, not leaving their side. It might have been because Billie heard them speaking Hebrew, he told them.

Speaking to Israeli television, reserve soldier Aviad Shapira said he found Billie among the rubble and called out to her. “I said ‘shalom’ and she jumped on me,” he said.He had a feeling that she didn’t belong in Gaza and that there was a story behind her, Shapira said. He brought the dog to a veterinarian and found the family’s contact information on a chip inside the animal.

Stroking Billie on her lap, Dancyg says it will take time to see how the odyssey has affected her. Billie appears happy to be home, but she seems disoriented and has lost weight, Dancyg said.Rachel Dancyg holds her dog, Billie, on Wednesday, April 16, 2025. Israeli soldiers found Billie in the Gaza Strip, 18 months after she disappeared during Hamas’ attack on Dancyg’s Kibbutz of Nir Oz, in Binyamina, Israel. (AP Photo/Ariel Schalit)