内容摘要：The 11-month-old has a mutation of the PPFIBP1 gene which means he is blind, has frequent seizures and is unlikely to ever walk or talk.

The 11-month-old has a mutation of the PPFIBP1 gene which means he is blind, has frequent seizures and is unlikely to ever walk or talk.

On check-ups, it says there is "false narrative" that six-monthly check-ups are necessary for everyone and that by giving people with healthy teeth a check-up less often, it will open up access for others.NICE guidelines say intervals between check-ups "should be determined specifically for each patient" and the longest interval for adults should be 18-24 months.

But Dr Lauren Harrhy from the BDA said she was concerned that people may end up waiting much longer, with "most people" benefiting from regular checks.Dr Harrhy, who runs a practice in Pontypool, Torfaen, said: "If we are always having patients into the practice who need lots of work done and they are not able to be put back into the central database, there is a saturation point and at which point, access into dental practices will cease."Our main concerns are we will have an overall reduction in the continuity of care... and we may find that dentists leave NHS dentistry which has been a trend over recent years anyway."

Dentists also say the proposals offer no extra money to fund the changes.But Miles said investment in dentistry had increased year on year.

"This isn't a contract we have drawn up from thin air, it is based on years worth of work, it's 13 months of negotiations with the BDA itself," he said.

"No contract gives everybody exactly what they want but I am absolutely confident that for everybody - for patients, for dentists, for the NHS, for the government - this is a step forward."The initial Portuguese investigation failed to preserve the scene adequately, so the opportunity to gather forensic evidence from Madeline McCann's room at the Ocean Club was lost. Long-term residents remember joining in uncoordinated and ad-hoc searches of the town.

The Metropolitan Police investigation that began in 2011 built to a peak in 2014, with substantial searches near Praia da Luz - but they did not appear to have any identifiable suspects.They had 60 people of interest, 38 of whom they were investigating. Portuguese prosecutors had allowed them to search only one of three sites they had asked for access to.

Everything changed in June 2020 when, out of the blue, the head prosecutor in Braunschweig in Germany, Hans Christian Wolters, saidWorking with the Bundeskriminalamt (BKA), the German equivalent of the FBI, he said he had identified a suspect, later identified as Christian Brückner.